HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: EPHA5 (P54756)
Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)
Gene: EPHA5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 781 Hs			1 1037
+	Hs
		542243 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		EPHA5_HUMAN (1-1037): 0: 1374: 100.00
+	Hs
		717105 CTNB1_HUMAN (1-781): 0: 626: 100.00		EPHA7_HUMAN (37-1035): 0: 1222: 62.69
+	Hs
		665553 CTNB1_HUMAN (1-781): 0: 626: 100.00		EPHB2_HUMAN (60-1034): 0: 1209: 56.80
+	Hs
		665443 CTNB1_HUMAN (1-781): 0: 626: 100.00		EPHA8_HUMAN (60-1036): 0: 1155: 57.78
+	Hs
		665156 CTNB1_HUMAN (1-781): 0: 626: 100.00		EPHA2_HUMAN (58-1037): 0: 1105: 50.86
+	Hs
		542244 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		EPHA4_HUMAN (33-1035): 0: 1223: 62.04
+	Hs
		542333 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		EPHA7_HUMAN (37-1035): 0: 1222: 62.69
+	Hs
		542198 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		EPHB2_HUMAN (60-1034): 0: 1209: 56.80
+	Dm
		578636 ARM_DROME (1-780): 9.15e-160: 486: 64.49		Q0KIF4_DROME (55-1026): 0: 913: 40.47
+	Hs
		131383 IMA4_HUMAN (220-681): 6.79e-68: 235: 15.25		EPHA2_HUMAN (58-1037): 0: 1105: 50.86
+	Hs
		853217 IMA1_HUMAN (237-675): 3.54e-66: 231: 18.54		EPHB4_HUMAN (44-1031): 0: 1056: 47.11
+	Hs
		435557 CTNB1_HUMAN (1-781): 0: 626: 100.00		IGF1R_HUMAN (294-1017): 7.97e-145: 469: 23.00
+	Rn
		544931 CTNB1_RAT (1-781): 0: 625: 99.74		INSR_RAT (400-940): 1.09e-142: 464: 29.88
+	Hs
		717022 CTNB1_HUMAN (1-781): 0: 626: 100.00		TYRO3_HUMAN (293-975): 8.48e-147: 462: 21.19
+	Hs
		435524 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		IGF1R_HUMAN (294-1017): 7.97e-145: 469: 23.00
+	Hs
		542203 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		UFO_HUMAN (290-1017): 4.06e-147: 463: 21.89
+	Hs
		433616 CTNB1_HUMAN (1-781): 0: 626: 100.00		LYN_HUMAN (659-933): 1.73e-65: 231: 43.68
+	Hs
		412054 CTNB1_HUMAN (1-781): 0: 626: 100.00		FYN_HUMAN (669-933): 3.12e-64: 229: 44.20
+	Hs
		433555 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		LYN_HUMAN (659-933): 1.73e-65: 231: 43.68
+	Mm
		546270 PLAK_MOUSE (8-752): 6.82e-156: 473: 66.62		INSR_MOUSE (372-515): 2.77e-11: 70: 17.50