HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: TYRO3 (Q06418)
Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)
Gene: TYRO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001764 - neuron migration GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0007155 - cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 781 Hs			1 890
+	Hs
		665553 CTNB1_HUMAN (1-781): 0: 626: 100.00		EPHB2_HUMAN (72-826): 1.04e-178: 546: 20.21
+	Hs
		716907 CTNB1_HUMAN (1-781): 0: 626: 100.00		EPHA5_HUMAN (125-818): 6.7e-176: 538: 20.30
+	Hs
		717105 CTNB1_HUMAN (1-781): 0: 626: 100.00		EPHA7_HUMAN (116-823): 2.21e-172: 528: 20.33
+	Hs
		665443 CTNB1_HUMAN (1-781): 0: 626: 100.00		EPHA8_HUMAN (116-808): 3.82e-166: 511: 20.03
+	Hs
		665156 CTNB1_HUMAN (1-781): 0: 626: 100.00		EPHA2_HUMAN (116-832): 1.86e-165: 509: 21.01
+	Rn
		544931 CTNB1_RAT (1-781): 0: 625: 99.74		INSR_RAT (232-788): 7.04e-127: 416: 27.65
+	Hs
		542198 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		EPHB2_HUMAN (72-826): 1.04e-178: 546: 20.21
+	Hs
		542243 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		EPHA5_HUMAN (125-818): 6.7e-176: 538: 20.30
+	Hs
		542244 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		EPHA4_HUMAN (119-820): 7.18e-173: 528: 20.61
+	Hs
		542333 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		EPHA7_HUMAN (116-823): 2.21e-172: 528: 20.33
+	Hs
		441449 CTNB1_HUMAN (1-781): 0: 626: 100.00		MET_HUMAN (495-790): 3.89e-65: 240: 41.67
+	Hs
		435557 CTNB1_HUMAN (1-781): 0: 626: 100.00		IGF1R_HUMAN (333-779): 3.39e-61: 228: 32.53
+	Hs
		434143 CTNB1_HUMAN (1-781): 0: 626: 100.00		RET_HUMAN (514-790): 1.89e-55: 210: 39.93
+	Hs
		337371 CTNB1_HUMAN (1-781): 0: 626: 100.00		ABL1_HUMAN (519-878): 6.21e-54: 205: 36.76
+	Hs
		713763 CTNB1_HUMAN (1-781): 0: 626: 100.00		RYK_HUMAN (503-782): 8.78e-55: 202: 37.50
+	Hs
		507882 CTNB1_HUMAN (1-781): 0: 626: 100.00		FGFR1_HUMAN (6-230): 2.63e-19: 95.6: 18.22
+	Hs
		435524 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		IGF1R_HUMAN (333-779): 3.39e-61: 228: 32.53
+	Hs
		542212 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		RYK_HUMAN (503-782): 8.78e-55: 202: 37.50
+	Hs
		507826 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		FGFR1_HUMAN (6-230): 2.63e-19: 95.6: 18.22
+	Hs
		542203 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		UFO_HUMAN (6-344): 1.91e-14: 79.8: 14.56