HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: PITX2 (Q99697)
Pituitary homeobox 2 (ALL1-responsive protein ARP1) (Homeobox protein PITX2) (Paired-like homeodomain transcription factor 2) (RIEG bicoid-related homeobox transcription factor) (Solurshin)
Gene: PITX2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

The method score is based on:

Property	Details
Experiments	12464179, 15728254, 19174163
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003151 - outflow tract morphogenesis GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex and 6 others more... GO:0005737 - cytoplasm GO:0008284 - positive regulation of cell population proliferation GO:0035315 - hair cell differentiation GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	781
Hs

1	317

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024