HitPredict

Interactor 1: CDC16 (B3DNN5)
Anaphase-promoting complex subunit 6 (Cell division cycle protein 16 homolog) (CDC16 homolog) (Cyclosome subunit 6) (Protein NOMEGA)
Gene: APC6

Interactor 2: APC7 (Q8VY89)
Anaphase-promoting complex subunit 7 (Cyclosome subunit 7)
Gene: APC7

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	20706207
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	TPR_16~TPR_19
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0007049 - cell cycle GO:0016567 - protein ubiquitination GO:0045842 - positive regulation of mitotic metaphase/anaphase transition GO:0051301 - cell division
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 543 At			1 558
+	At
		71743 CDC16_ARATH (1-543): 2.83e-91: 291: 100.00		CD27B_ARATH (210-538): 6.26e-67: 232: 18.98
+	Hs
		175291 OGT1_HUMAN (315-542): 1.92e-31: 131: 15.79		APC7_HUMAN (1-557): 2.92e-71: 240: 26.82
+	At
		989582 CD27A_ARATH (282-540): 1.53e-22: 103: 14.50		APC7_ARATH (1-558): 3e-80: 264: 100.00
+	At
		1257915 CDC23_ARATH (134-541): 7.68e-22: 100: 13.77		APC7_ARATH (1-558): 3e-80: 264: 100.00
+	At
		71751 CDC16_ARATH (1-543): 2.83e-91: 291: 100.00		CDC23_ARATH (283-549): 5.01e-12: 70.6: 12.96
+	Hs
		672848 Q5T8C6_HUMAN (97-529): 9.17e-74: 243: 30.25		CDC27_HUMAN (1-244): 5.19e-25: 111: 10.36
+	At
		1228171 CDC23_ARATH (134-541): 7.68e-22: 100: 13.77		CD27B_ARATH (210-538): 6.26e-67: 232: 18.98
+	Hs
		1356109 CDC23_HUMAN (31-360): 2.4e-18: 90.2: 9.69		APC7_HUMAN (1-557): 2.92e-71: 240: 26.82
+	Hs
		174451 OGT1_HUMAN (315-542): 1.92e-31: 131: 15.79		OGT1_HUMAN (7-413): 2.15e-49: 185: 11.42
+	Xl
		1151586 Q8AVF0_XENLA (36-539): 2.07e-56: 199: 16.96		Q6GQ04_XENLA (16-282): 3.37e-23: 106: 11.59
+	Dm
		1363028 Q9VCN6_DROME (238-533): 4.6e-44: 168: 33.45		Q9VS37_DROME (73-415): 1.2e-31: 132: 12.47
+	Sc
		561105 CDC23_YEAST (132-506): 4.24e-28: 120: 16.45		CDC23_YEAST (13-402): 3.93e-23: 105: 10.40
+	Sc
		454891 CDC23_YEAST (132-506): 4.24e-28: 120: 16.45		CDC16_YEAST (222-545): 5.11e-21: 99.5: 15.27
+	Xl
		1151584 Q7T0N9_XENLA (134-541): 9.99e-24: 107: 11.98		Q6GQ04_XENLA (16-282): 3.37e-23: 106: 11.59
+	Hs
		672916 CDC23_HUMAN (31-360): 2.4e-18: 90.2: 9.69		CDC27_HUMAN (1-244): 5.19e-25: 111: 10.36
+	Hs
		1024250 IFT88_HUMAN (185-542): 6.11e-21: 99.1: 10.17		IFT88_HUMAN (150-551): 1.43e-21: 101: 8.55
+	Hs
		1356108 CDC23_HUMAN (31-360): 2.4e-18: 90.2: 9.69		CDC23_HUMAN (179-549): 4.08e-23: 105: 14.21
+	Sc
		561118 CDC23_YEAST (132-506): 4.24e-28: 120: 16.45		CDC27_YEAST (224-462): 2.47e-12: 71.8: 18.60
+	Hs
		1023015 CDC23_HUMAN (31-360): 2.4e-18: 90.2: 9.69		CDC16_HUMAN (37-326): 4.67e-10: 64.4: 9.77