HitPredict

Interactor 1: CDC16 (B3DNN5)
Anaphase-promoting complex subunit 6 (Cell division cycle protein 16 homolog) (CDC16 homolog) (Cyclosome subunit 6) (Protein NOMEGA)
Gene: APC6

Interactor 2: CDC23 (Q9STS3)
Anaphase-promoting complex subunit 8 (Cell division cycle protein 23 homolog) (CDC23 homolog) (Cyclosome subunit 8)
Gene: APC8

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	20706207
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC3~TPR_11, ANAPC3~TPR_8, TPR_1~TPR_11, TPR_1~TPR_8, TPR_11~TPR_16, TPR_16~TPR_8, TPR_10~TPR_7, TPR_7~TPR_8, TPR_11~TPR_8, TPR_8~TPR_8
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0007049 - cell cycle GO:0016567 - protein ubiquitination GO:0031145 - anaphase-promoting complex-dependent catabolic process GO:0045842 - positive regulation of mitotic metaphase/anaphase transition and 1 others more... GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 At			1 579
+	At
		71745 CDC16_ARATH (1-543): 2.83e-91: 291: 100.00		APC7_ARATH (67-572): 2.35e-54: 195: 17.55
+	At
		71743 CDC16_ARATH (1-543): 2.83e-91: 291: 100.00		CD27B_ARATH (346-579): 2.44e-18: 91.1: 14.53
+	Hs
		672848 Q5T8C6_HUMAN (97-529): 9.17e-74: 243: 30.25		CDC27_HUMAN (71-338): 8.44e-26: 114: 11.55
+	Sc
		561105 CDC23_YEAST (132-506): 4.24e-28: 120: 16.45		CDC23_YEAST (7-566): 1.5e-53: 194: 27.98
+	Xl
		1151586 Q8AVF0_XENLA (36-539): 2.07e-56: 199: 16.96		Q6GQ04_XENLA (71-341): 1.74e-23: 107: 10.71
+	At
		989582 CD27A_ARATH (282-540): 1.53e-22: 103: 14.50		APC7_ARATH (67-572): 2.35e-54: 195: 17.55
+	At
		1257915 CDC23_ARATH (134-541): 7.68e-22: 100: 13.77		APC7_ARATH (67-572): 2.35e-54: 195: 17.55
+	Dm
		1363028 Q9VCN6_DROME (238-533): 4.6e-44: 168: 33.45		Q9VS37_DROME (318-578): 3.27e-22: 103: 14.18
+	Hs
		1024250 IFT88_HUMAN (185-542): 6.11e-21: 99.1: 10.17		IFT88_HUMAN (97-519): 5.1e-32: 133: 10.75
+	Hs
		175291 OGT1_HUMAN (315-542): 1.92e-31: 131: 15.79		APC7_HUMAN (175-579): 3.87e-21: 99.2: 10.25
+	Hs
		174451 OGT1_HUMAN (315-542): 1.92e-31: 131: 15.79		OGT1_HUMAN (2-223): 4.44e-17: 87.2: 9.91
+	Xl
		1151584 Q7T0N9_XENLA (134-541): 9.99e-24: 107: 11.98		Q6GQ04_XENLA (71-341): 1.74e-23: 107: 10.71
+	Sc
		561118 CDC23_YEAST (132-506): 4.24e-28: 120: 16.45		CDC27_YEAST (92-405): 8.01e-19: 92.6: 11.98
+	Hs
		672916 CDC23_HUMAN (31-360): 2.4e-18: 90.2: 9.69		CDC27_HUMAN (71-338): 8.44e-26: 114: 11.55
+	Xl
		1150214 Q6DDX5_XENLA (131-542): 2.53e-18: 90.2: 12.98		Q6GQ04_XENLA (71-341): 1.74e-23: 107: 10.71
+	Sc
		454891 CDC23_YEAST (132-506): 4.24e-28: 120: 16.45		CDC16_YEAST (212-578): 1.99e-13: 75.3: 10.27
+	At
		1228171 CDC23_ARATH (134-541): 7.68e-22: 100: 13.77		CD27B_ARATH (346-579): 2.44e-18: 91.1: 14.53
+	Hs
		1356109 CDC23_HUMAN (31-360): 2.4e-18: 90.2: 9.69		APC7_HUMAN (175-579): 3.87e-21: 99.2: 10.25
+	Hs
		1356108 CDC23_HUMAN (31-360): 2.4e-18: 90.2: 9.69		CDC23_HUMAN (275-579): 9.2e-10: 63.3: 12.91
+	Hs
		1023015 CDC23_HUMAN (31-360): 2.4e-18: 90.2: 9.69		CDC16_HUMAN (70-345): 2.04e-09: 62.2: 9.56