HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	15009096
Identification Methods	biochemical
Interaction Type	association

Property	Details
Interacting Pfam domains	Histone~zf-C3HC4_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 140
+	Hs
		717680 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		H31_HUMAN (5-134): 1.29e-52: 164: 48.86
+	Hs
		717875 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		H31T_HUMAN (5-134): 1.01e-51: 162: 48.09
+	Hs
		935201 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		H31_HUMAN (5-134): 1.29e-52: 164: 48.86
+	Hs
		1086305 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		H31T_HUMAN (5-134): 1.01e-51: 162: 48.09
+	Hs
		935183 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		H31_HUMAN (5-134): 1.29e-52: 164: 48.86
+	Hs
		952606 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		H33_HUMAN (5-134): 1.57e-51: 161: 49.62
+	Hs
		952593 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		H33_HUMAN (5-134): 1.57e-51: 161: 49.62
+	Hs
		584928 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		H31_HUMAN (5-134): 1.29e-52: 164: 48.86
+	Hs
		828356 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00
+	Hs
		935154 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		H31_HUMAN (5-134): 1.29e-52: 164: 48.86
+	Hs
		1086286 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		H31T_HUMAN (5-134): 1.01e-51: 162: 48.09
+	Hs
		952576 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		H33_HUMAN (5-134): 1.57e-51: 161: 49.62
+	Hs
		1157225 TRIM4_HUMAN (10-198): 5.23e-47: 167: 17.05		H3C_HUMAN (5-134): 5.15e-52: 162: 47.69
+	Hs
		828206 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00
+	Hs
		934691 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		H31_HUMAN (5-134): 1.29e-52: 164: 48.86
+	Hs
		987976 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		H31T_HUMAN (5-134): 1.01e-51: 162: 48.09
+	Hs
		952292 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		H33_HUMAN (5-134): 1.57e-51: 161: 49.62
+	Hs
		282622 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		H33_HUMAN (5-134): 1.57e-51: 161: 49.62