HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: TBB4B (P68371)
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Gene: TUBB4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 445
+	Hs
		717790 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		TBB3_HUMAN (1-443): 0: 714: 93.23
+	Hs
		428047 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		718153 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		TBB6_HUMAN (1-432): 0: 706: 92.36
+	Hs
		1037380 TRIM6_HUMAN (5-189): 2.83e-49: 173: 16.67		TBB3_HUMAN (1-443): 0: 714: 93.23
+	Hs
		933939 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		TBB4B_HUMAN (1-427): 0: 711: 100.00
+	Hs
		1046552 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		TBB2A_HUMAN (1-430): 0: 707: 97.67
+	Xl
		1125748 CHFR_XENLA (3-152): 1.29e-33: 132: 19.87		TBB5_XENLA (1-429): 0: 711: 98.37
+	Hs
		282485 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		282615 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		TBB4B_HUMAN (1-427): 0: 711: 100.00