HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	26468281, 36089195
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~zf-C3HC4_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 136
+	Hs
		717875 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		717557 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		935201 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		1086305 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		935183 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		952606 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		952593 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		584928 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		935154 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		1086286 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		952576 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		1157225 TRIM4_HUMAN (10-198): 5.23e-47: 167: 17.05		H3C_HUMAN (1-136): 5.49e-58: 177: 93.38
+	Hs
		828356 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		934691 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		987976 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		952292 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		282622 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		828206 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00