HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: DYST (Q03001)
Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)
Gene: DST

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 7570
+	Hs
		513833 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		DMD_HUMAN (383-1643): 8.98e-27: 124: 11.75
+	Hs
		521481 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00
+	Hs
		717709 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95
+	Hs
		718318 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MACF1_HUMAN (351-1936): 4.95e-21: 105: 11.05
+	Hs
		164573 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN2_HUMAN (5708-7163): 4.91e-17: 92.5: 14.91
+	Hs
		717542 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		UTRN_HUMAN (264-1530): 1.26e-14: 84.8: 9.65
+	Hs
		717799 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42
+	Hs
		718187 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN4_HUMAN (6019-7220): 1.47e-12: 77.8: 14.47
+	Hs
		717848 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19
+	Hs
		717606 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		EPIPL_HUMAN (1651-1891): 1.02e-10: 71.7: 20.73
+	Hs
		718032 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SYNE1_HUMAN (147-1832): 6.65e-10: 69: 8.83
+	Hs
		521464 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00
+	Hs
		584968 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19
+	Hs
		1244129 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		SYNE1_HUMAN (147-1832): 6.65e-10: 69: 8.83
+	Hs
		282506 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00
+	Hs
		282627 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95
+	Hs
		282645 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42
+	Hs
		963368 DTX3_HUMAN (17-62): 3.98e-10: 62.2: 39.13		SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95
+	Hs
		282514 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		DESP_HUMAN (1555-1738): 2.9e-09: 67: 28.50