HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: PRDX4 (Q13162)
Peroxiredoxin-4 (EC 1.11.1.24) (Antioxidant enzyme AOE372) (AOE37-2) (Peroxiredoxin IV) (Prx-IV) (Thioredoxin peroxidase AO372) (Thioredoxin-dependent peroxide reductase A0372) (Thioredoxin-dependent peroxiredoxin 4)
Gene: PRDX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	24457600, 34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 271
+	Hs
		670898 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PRDX3_HUMAN (29-271): 1.53e-112: 326: 54.44
+	Hs
		685624 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PRDX2_HUMAN (74-271): 2.45e-105: 305: 68.69
+	Hs
		717744 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PRDX1_HUMAN (74-269): 7.22e-102: 297: 68.53
+	Hs
		989274 TRI26_HUMAN (5-210): 1e-49: 175: 16.59		PRDX1_HUMAN (74-269): 7.22e-102: 297: 68.53
+	Hs
		989385 TRIM4_HUMAN (10-198): 5.23e-47: 167: 17.05		PRDX1_HUMAN (74-269): 7.22e-102: 297: 68.53
+	Hs
		282549 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		PRDX2_HUMAN (74-271): 2.45e-105: 305: 68.69
+	Hs
		282632 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		PRDX1_HUMAN (74-269): 7.22e-102: 297: 68.53