HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: NFIX (Q14938)
Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)
Gene: NFIX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	34316702
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 502
+	Hs
		717763 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47
+	Hs
		443138 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43
+	Hs
		1060362 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00
+	Hs
		987973 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00
+	Hs
		443239 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43
+	Hs
		135151 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		NFIB_HUMAN (1-419): 4.58e-101: 311: 58.69
+	Hs
		124060 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		SPT5H_HUMAN (144-357): 1.74e-12: 71.9: 13.60
+	Hs
		1304153 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		OGFR_HUMAN (174-467): 5.43e-11: 66.9: 12.59
+	Hs
		987995 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		KMT2C_HUMAN (197-498): 9.61e-09: 60.4: 9.61