HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 2229
+	Hs
		718326 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		718364 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12
+	Hs
		717810 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		EIF3A_HUMAN (962-1409): 3.68e-26: 120: 14.63
+	Hs
		718055 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		554277 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MUC1_HUMAN (92-987): 9.05e-19: 96: 9.37
+	Hs
		718128 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MINT_HUMAN (296-2220): 2.45e-17: 91.8: 8.49
+	Hs
		717965 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MICA3_HUMAN (780-1521): 5.12e-11: 70.6: 11.89
+	Hs
		717549 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24
+	Hs
		717688 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MAP1A_HUMAN (8-661): 1.5e-10: 69.3: 10.23
+	Hs
		1019387 TRI26_HUMAN (5-210): 1e-49: 175: 16.59		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		1049625 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		EIF3A_HUMAN (962-1409): 3.68e-26: 120: 14.63
+	Hs
		1300927 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Hs
		1264788 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		1056961 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56
+	Hs
		585039 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Hs
		1223389 TRI22_HUMAN (1-198): 2.92e-50: 175: 14.56		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Hs
		1300908 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Hs
		988011 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Hs
		282654 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56