HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: HELZ2 (Q9BYK8)
3'-5' exoribonuclease HELZ2 (EC 3.1.13.1) (ATP-dependent RNA helicase PRIC285) (EC 3.6.4.13) (Helicase with zinc finger 2, transcriptional coactivator) (Helicase with zinc finger domain 2) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein)
Gene: HELZ2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	24457600, 34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 2896
+	Hs
		718003 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		DI3L2_HUMAN (1222-2042): 0: 627: 20.46
+	Hs
		718072 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		RENT1_HUMAN (2148-2891): 0: 606: 24.35
+	Hs
		718215 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MOV10_HUMAN (2257-2886): 7.48e-121: 411: 21.93
+	Hs
		1272327 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		RENT1_HUMAN (2148-2891): 0: 606: 24.35
+	Hs
		1272312 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		RENT1_HUMAN (2148-2891): 0: 606: 24.35
+	Hs
		718432 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		MOV10_HUMAN (2257-2886): 7.48e-121: 411: 21.93
+	Hs
		1304117 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		MOV10_HUMAN (2257-2886): 7.48e-121: 411: 21.93
+	Hs
		988025 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		MOV10_HUMAN (2257-2886): 7.48e-121: 411: 21.93