HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: NANOG (Q9H9S0)
Homeobox protein NANOG (Homeobox transcription factor Nanog) (hNanog)
Gene: NANOG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26687479
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0010468 - regulation of gene expression
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 326 Hs			1 305
+	Hs
		595583 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		HXA5_HUMAN (2-165): 8.34e-36: 131: 20.69
+	Hs
		201868 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		HXA3_HUMAN (41-216): 2e-33: 128: 24.86
+	Hs
		718428 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		NANOG_HUMAN (1-305): 3.02e-64: 206: 100.00
+	Hs
		1311543 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		NANOG_HUMAN (1-305): 3.02e-64: 206: 100.00
+	Hs
		585071 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		NANOG_HUMAN (1-305): 3.02e-64: 206: 100.00
+	Hs
		1304113 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		NANOG_HUMAN (1-305): 3.02e-64: 206: 100.00
+	Mm
		1194679 PCGF6_MOUSE (2-235): 3.79e-60: 198: 35.54		NANOG_MOUSE (1-303): 7.62e-40: 143: 54.98
+	Hs
		641552 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		641545 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		679164 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		TLX1_HUMAN (26-221): 2.65e-30: 118: 23.47
+	Mm
		1194680 RING2_MOUSE (7-227): 5.77e-50: 171: 16.61		NANOG_MOUSE (1-303): 7.62e-40: 143: 54.98
+	Hs
		211952 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		TLX3_HUMAN (88-157): 1.29e-25: 104: 42.86
+	Hs
		641464 PCGF5_HUMAN (1-228): 9.27e-56: 183: 30.44		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		679129 PCGF5_HUMAN (1-228): 9.27e-56: 183: 30.44		TLX1_HUMAN (26-221): 2.65e-30: 118: 23.47
+	Hs
		213349 PCGF5_HUMAN (1-228): 9.27e-56: 183: 30.44		TLX2_HUMAN (76-157): 1.26e-27: 110: 37.35
+	Hs
		641538 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		679160 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		TLX1_HUMAN (26-221): 2.65e-30: 118: 23.47
+	Hs
		211899 PCGF5_HUMAN (1-228): 9.27e-56: 183: 30.44		TLX3_HUMAN (88-157): 1.29e-25: 104: 42.86
+	Hs
		641384 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		PAX6_HUMAN (49-293): 3.5e-30: 119: 14.17
+	Hs
		211843 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		TLX3_HUMAN (88-157): 1.29e-25: 104: 42.86