HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: SCML1 (Q9UN30)
Sex comb on midleg-like protein 1
Gene: SCML1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	27705803
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 326 Hs			1 329
+	Hs
		718440 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		SCML1_HUMAN (1-329): 1.77e-123: 359: 100.00
+	Hs
		718330 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SCML2_HUMAN (109-325): 7.08e-47: 170: 31.44
+	Hs
		718098 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SCMH1_HUMAN (131-325): 1.54e-46: 168: 30.85
+	Hs
		1220909 R4GMX3_HUMAN (1-326): 5.65e-157: 449: 100.00		PHC2_HUMAN (146-324): 1.16e-33: 133: 19.23
+	Hs
		717684 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PHC1_HUMAN (189-324): 4.41e-34: 134: 26.47
+	Hs
		717999 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PHC2_HUMAN (146-324): 1.16e-33: 133: 19.23
+	Hs
		718028 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PHC3_HUMAN (162-324): 7.6e-33: 130: 21.47
+	Mm
		639480 BMI1_MOUSE (1-326): 2.15e-150: 426: 96.93		PHC2_MOUSE (159-324): 1.09e-33: 133: 21.30
+	Mm
		639473 BMI1_MOUSE (1-326): 2.15e-150: 426: 96.93		PHC1_MOUSE (189-324): 1.76e-33: 132: 27.21
+	Mm
		639476 BMI1_MOUSE (1-326): 2.15e-150: 426: 96.93		PHC3_MOUSE (162-324): 2.01e-33: 132: 21.47
+	Dr
		1225025 BMI1A_DANRE (1-326): 9.35e-128: 369: 81.29		PHC2_DANRE (146-324): 4.31e-38: 145: 24.34
+	Hs
		718418 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		SCMH1_HUMAN (131-325): 1.54e-46: 168: 30.85
+	Dr
		1186373 BMI1B_DANRE (1-322): 4e-124: 360: 77.23		PHC2_DANRE (146-324): 4.31e-38: 145: 24.34
+	Hs
		718390 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		PHC1_HUMAN (189-324): 4.41e-34: 134: 26.47
+	Hs
		718408 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		PHC2_HUMAN (146-324): 1.16e-33: 133: 19.23
+	Hs
		718412 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		PHC3_HUMAN (162-324): 7.6e-33: 130: 21.47
+	Mm
		620794 PCGF2_MOUSE (1-320): 5.49e-113: 332: 61.06		PHC2_MOUSE (159-324): 1.09e-33: 133: 21.30
+	Mm
		620786 PCGF2_MOUSE (1-320): 5.49e-113: 332: 61.06		PHC1_MOUSE (189-324): 1.76e-33: 132: 27.21
+	Mm
		620790 PCGF2_MOUSE (1-320): 5.49e-113: 332: 61.06		PHC3_MOUSE (162-324): 2.01e-33: 132: 21.47
+	Hs
		943064 PCGF3_HUMAN (4-228): 4.43e-72: 225: 34.03		PHC1_HUMAN (189-324): 4.41e-34: 134: 26.47