HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: SCML2 (Q9UQR0)
Sex comb on midleg-like protein 2
Gene: SCML2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25605328
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0031519 - PcG protein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 326 Hs			1 700
+	Hs
		718083 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		LMBL2_HUMAN (2-547): 1.83e-103: 333: 17.64
+	Hs
		1220909 R4GMX3_HUMAN (1-326): 5.65e-157: 449: 100.00		PHC2_HUMAN (211-697): 1.07e-85: 289: 15.99
+	Hs
		717999 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PHC2_HUMAN (211-697): 1.07e-85: 289: 15.99
+	Mm
		639480 BMI1_MOUSE (1-326): 2.15e-150: 426: 96.93		PHC2_MOUSE (211-697): 5.59e-81: 276: 15.73
+	Hs
		718416 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		LMBL2_HUMAN (2-547): 1.83e-103: 333: 17.64
+	Dr
		1225025 BMI1A_DANRE (1-326): 9.35e-128: 369: 81.29		PHC2_DANRE (253-697): 2.86e-78: 269: 17.04
+	Hs
		718408 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		PHC2_HUMAN (211-697): 1.07e-85: 289: 15.99
+	Dr
		1186373 BMI1B_DANRE (1-322): 4e-124: 360: 77.23		PHC2_DANRE (253-697): 2.86e-78: 269: 17.04
+	Hs
		717684 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PHC1_HUMAN (455-696): 4.09e-47: 181: 21.57
+	Mm
		639473 BMI1_MOUSE (1-326): 2.15e-150: 426: 96.93		PHC1_MOUSE (220-696): 2.89e-48: 185: 13.94
+	Hs
		718028 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PHC3_HUMAN (445-697): 4.59e-41: 163: 20.30
+	Mm
		639476 BMI1_MOUSE (1-326): 2.15e-150: 426: 96.93		PHC3_MOUSE (445-697): 5.73e-42: 166: 20.30
+	Hs
		718311 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SCML1_HUMAN (471-698): 6.13e-32: 128: 29.54
+	Hs
		718098 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SCMH1_HUMAN (7-131): 9.67e-23: 105: 32.03
+	Hs
		718390 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		PHC1_HUMAN (455-696): 4.09e-47: 181: 21.57
+	Mm
		620786 PCGF2_MOUSE (1-320): 5.49e-113: 332: 61.06		PHC1_MOUSE (220-696): 2.89e-48: 185: 13.94
+	Hs
		718412 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		PHC3_HUMAN (445-697): 4.59e-41: 163: 20.30
+	Mm
		620790 PCGF2_MOUSE (1-320): 5.49e-113: 332: 61.06		PHC3_MOUSE (445-697): 5.73e-42: 166: 20.30
+	Hs
		718440 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		SCML1_HUMAN (471-698): 6.13e-32: 128: 29.54
+	Hs
		718418 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		SCMH1_HUMAN (7-131): 9.67e-23: 105: 32.03