HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: UBP15 (Q9Y4E8)
Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Unph-2) (Unph4)
Gene: USP15

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	31921558
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016604 - nuclear body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 326 Hs			1 981
+	Hs
		717585 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		UBP11_HUMAN (9-946): 0: 661: 43.58
+	Hs
		585101 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		UBP15_HUMAN (1-981): 0: 859: 100.00
+	Hs
		1318721 TRIM5_HUMAN (9-190): 3.01e-48: 170: 14.89		UBP15_HUMAN (1-981): 0: 859: 100.00
+	Hs
		1377848 TRI17_HUMAN (10-198): 2.34e-44: 159: 15.42		UBP15_HUMAN (1-981): 0: 859: 100.00
+	Hs
		718382 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		UBP11_HUMAN (9-946): 0: 661: 43.58
+	Hs
		584941 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		UBP4_HUMAN (1-981): 0: 794: 55.38
+	Hs
		850161 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		UBP11_HUMAN (9-946): 0: 661: 43.58
+	Hs
		850010 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		UBP11_HUMAN (9-946): 0: 661: 43.58
+	Hs
		301359 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		UBP19_HUMAN (197-960): 5.82e-149: 477: 29.50
+	Hs
		301435 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		UBP19_HUMAN (197-960): 5.82e-149: 477: 29.50
+	Hs
		718324 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		UBP22_HUMAN (772-933): 1.82e-57: 208: 32.20
+	Hs
		1198275 TRIM4_HUMAN (10-198): 5.23e-47: 167: 17.05		UBP37_HUMAN (126-958): 3.63e-87: 302: 14.10
+	Hs
		1316715 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		UBP21_HUMAN (570-935): 1.17e-66: 236: 20.32
+	Hs
		271183 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		UBP2_HUMAN (647-935): 1.13e-62: 226: 25.09
+	Hs
		1318717 TRIM5_HUMAN (9-190): 3.01e-48: 170: 14.89		UBP21_HUMAN (570-935): 1.17e-66: 236: 20.32
+	Hs
		271032 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		UBP2_HUMAN (647-935): 1.13e-62: 226: 25.09
+	Hs
		271189 TRIM5_HUMAN (9-190): 3.01e-48: 170: 14.89		UBP2_HUMAN (647-935): 1.13e-62: 226: 25.09
+	Hs
		271195 TRI39_HUMAN (9-198): 1.36e-45: 163: 16.50		UBP2_HUMAN (647-935): 1.13e-62: 226: 25.09
+	Hs
		271184 TRI34_HUMAN (11-190): 1.8e-44: 160: 15.51		UBP2_HUMAN (647-935): 1.13e-62: 226: 25.09
+	Hs
		1257026 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		UBP33_HUMAN (400-652): 3.18e-25: 115: 12.38