HitPredict

Interactor 1: PCGF2 (P35227)
Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144)
Gene: PCGF2

Interactor 2: RING1 (Q06587)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein)
Gene: RING1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 21516116, 27705803, 32296183, 24981860, 22325352, 28514442, 33961781, 17936708, 19636380, 22493164, unassigned1304, 20601937
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, validated two hybrid, tandem affinity purification, two hybrid array, two hybrid prey pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RAWUL~RAWUL, zf-C3HC4_2~zf-C3HC4_2
Common GO terms GO:0001739 - sex chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006338 - chromatin remodeling
GO:0009952 - anterior/posterior pattern specification
and 3 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Hs

1 406
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Last updated: 15 Jul 2024