HitPredict

Interactor 1: PCGF2 (P35227)
Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144)
Gene: PCGF2

Interactor 2: UBE2U (Q5VVX9)
Ubiquitin-conjugating enzyme E2 U (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme U) (Ubiquitin carrier protein U) (Ubiquitin-protein ligase U)
Gene: UBE2U

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.80	0.625

Property	Details
Experiments	19690564
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 344 Hs			1 321
+	Hs
		1138911 PCGF1_HUMAN (2-232): 1.01e-61: 199: 35.42		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		1138915 PCGF6_HUMAN (2-227): 3.54e-58: 193: 35.47		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		1138906 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		718384 PCGF2_HUMAN (1-344): 8.96e-118: 345: 100.00		UB2D3_HUMAN (4-153): 1.55e-74: 227: 34.00
+	Hs
		718419 PCGF2_HUMAN (1-344): 8.96e-118: 345: 100.00		UB2E2_HUMAN (3-153): 5.78e-68: 212: 23.18
+	Hs
		717650 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		UB2D2_HUMAN (4-153): 8.78e-76: 230: 34.67
+	Hs
		717615 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		UB2D3_HUMAN (4-153): 1.55e-74: 227: 34.00
+	Hs
		895802 PCGF3_HUMAN (4-230): 3.51e-66: 210: 33.48		UB2D3_HUMAN (4-153): 1.55e-74: 227: 34.00
+	Hs
		895893 PCGF1_HUMAN (2-232): 1.01e-61: 199: 35.42		UB2D3_HUMAN (4-153): 1.55e-74: 227: 34.00
+	Hs
		1108530 PCGF3_HUMAN (4-230): 3.51e-66: 210: 33.48		UB2E3_HUMAN (3-153): 1.57e-67: 211: 24.50
+	Hs
		895898 PCGF6_HUMAN (2-227): 3.54e-58: 193: 35.47		UB2D3_HUMAN (4-153): 1.55e-74: 227: 34.00
+	Hs
		895830 PCGF5_HUMAN (1-221): 5.43e-53: 177: 31.88		UB2D3_HUMAN (4-153): 1.55e-74: 227: 34.00
+	Hs
		849421 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		UB2D1_HUMAN (4-153): 1.02e-75: 230: 30.00
+	Hs
		919836 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		UB2D2_HUMAN (4-153): 8.78e-76: 230: 34.67
+	Hs
		851832 PCGF5_HUMAN (1-221): 5.43e-53: 177: 31.88		UB2E1_HUMAN (3-153): 1.32e-66: 209: 25.17
+	Hs
		895890 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		UB2D3_HUMAN (4-153): 1.55e-74: 227: 34.00
+	Hs
		1297361 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		UB2E2_HUMAN (3-153): 5.78e-68: 212: 23.18
+	Hs
		1282333 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		UB2E3_HUMAN (3-153): 1.57e-67: 211: 24.50
+	Hs
		851877 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		UB2E1_HUMAN (3-153): 1.32e-66: 209: 25.17
+	Hs
		135938 PCGF3_HUMAN (4-230): 3.51e-66: 210: 33.48		UBE2C_HUMAN (9-145): 2.39e-20: 88.2: 35.77