HitPredict

Interactor 1: PCGF2 (P35227)
Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144)
Gene: PCGF2

Interactor 2: RYBP (Q8N488)
RING1 and YY1-binding protein (Apoptin-associating protein 1) (APAP-1) (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1)
Gene: RYBP

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.950

The method score is based on:

Property Details
Experiments 26186194, 27705803, 24981860, 33961781, 22325352, 28514442
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RAWUL~YAF2_RYBP
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006338 - chromatin remodeling
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 344
Hs

1 228
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024