Interactor 1: NOS2 (P35228)
Nitric oxide synthase, inducible (EC 1.14.13.39) (Hepatocyte NOS) (HEP-NOS) (Inducible NO synthase) (Inducible NOS) (iNOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2)
Gene: NOS2
Interactor 2: NOS2 (P35228)
Nitric oxide synthase, inducible (EC 1.14.13.39) (Hepatocyte NOS) (HEP-NOS) (Inducible NO synthase) (Inducible NOS) (iNOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2)
Gene: NOS2
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.90 | 1.00 | 0.952 |
The method score is based on:
Property | Details |
---|---|
Experiments | 11517317, 19737939, 23438482, 10074942, 18849972, 19364813, 14614131 |
Identification Methods | biochemical, x-ray crystallography, pull down, affinity chromatography technology, anti tag coimmunoprecipitation, comigration in gel electrophoresis |
Interaction Type | association, direct interaction, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | FAD_binding_1~FAD_binding_1, FAD_binding_1~Flavodoxin_1, FAD_binding_1~NAD_binding_1, Flavodoxin_1~Flavodoxin_1, Flavodoxin_1~NAD_binding_1, NAD_binding_1~NAD_binding_1, NO_synthase~NO_synthase |
Common GO terms | GO:0001666 - response to hypoxia GO:0001912 - positive regulation of leukocyte mediated cytotoxicity GO:0002227 - innate immune response in mucosa GO:0004517 - nitric-oxide synthase activity GO:0005516 - calmodulin binding and 44 others more... |
Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024