HitPredict

Interactor 1: PHB1 (P35232)
Prohibitin 1
Gene: PHB1

Interactor 2: RAB2A (P61019)
Ras-related protein Rab-2A (EC 3.6.5.2)
Gene: RAB2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 212
+	Hs
		718708 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		RB11A_HUMAN (3-212): 2.35e-83: 248: 46.67
+	Hs
		895239 PHB2_HUMAN (6-267): 1.38e-85: 259: 50.57		RAB2A_HUMAN (1-212): 1.36e-87: 258: 100.00
+	Hs
		914308 PHB2_HUMAN (6-267): 1.38e-85: 259: 50.57		RB11A_HUMAN (3-212): 2.35e-83: 248: 46.67
+	Hs
		591752 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		RAB4A_HUMAN (3-188): 6.91e-72: 219: 57.53
+	Mm
		931071 PHB1_MOUSE (1-272): 5.99e-92: 274: 99.63		RAB4B_MOUSE (3-188): 3.89e-71: 217: 55.91
+	Hs
		591992 PHB2_HUMAN (6-267): 1.38e-85: 259: 50.57		RAB4A_HUMAN (3-188): 6.91e-72: 219: 57.53
+	Mm
		192252 PHB2_MOUSE (6-267): 1.38e-85: 259: 50.57		RAB4B_MOUSE (3-188): 3.89e-71: 217: 55.91
+	Hs
		646159 STOM_HUMAN (1-265): 6.57e-68: 213: 17.91		RAB2A_HUMAN (1-212): 1.36e-87: 258: 100.00
+	Dm
		185571 Q9VWL0_DROME (4-266): 1.77e-65: 209: 21.05		RAB2_DROME (1-212): 1.05e-86: 256: 88.73
+	Dm
		185509 Q9VWL0_DROME (4-266): 1.77e-65: 209: 21.05		O18332_DROME (3-212): 6.15e-82: 244: 43.81
+	Hs
		73286 B4E2V5_HUMAN (34-265): 4.89e-57: 184: 19.57		RAB2A_HUMAN (1-212): 1.36e-87: 258: 100.00