Interactor 1: PHB1 (P35232)
Prohibitin 1
Gene: PHB1

Interactor 2: E2F1 (Q01094)
Transcription factor E2F1 (E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1) (Retinoblastoma-binding protein 3) (RBBP-3) (pRB-binding protein E2F-1)
Gene: E2F1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.55 0.694

The method score is based on:

Property Details
Experiments 14500729, 12065415, 10523633, 15141164, 14637159
Identification Methods affinity chromatography technology, pull down, coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006355 - regulation of DNA-templated transcription
and 3 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024