Interactor 1: MERL (P35240)
Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin)
Gene: NF2
Interactor 2: MERL (P35240)
Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin)
Gene: NF2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.86 | 1.00 | 0.930 |
The method score is based on:
Property | Details |
---|---|
Experiments | 24012335, 28205554, 11856822, 28514442, 11779178, 9537418 |
Identification Methods | affinity chromatography technology, fluorescent resonance energy transfer, x-ray crystallography, anti tag coimmunoprecipitation, two hybrid |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | ERM_C~ERM_C, ERM_C~FERM_C, ERM_C~FERM_M, ERM_helical~FERM_N, FERM_C~FERM_C, FERM_C~FERM_M, FERM_C~FERM_N, FERM_M~FERM_M, FERM_M~FERM_N, FERM_N~FERM_N |
Common GO terms | GO:0000165 - MAPK cascade GO:0001707 - mesoderm formation GO:0001953 - negative regulation of cell-matrix adhesion GO:0003779 - actin binding GO:0005178 - integrin binding and 49 others more... |
Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024