HitPredict

Interactor 1: MERL (P35240)
Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin)
Gene: NF2

Interactor 2: ASB9 (Q96DX5)
Ankyrin repeat and SOCS box protein 9 (ASB-9)
Gene: ASB9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 294
+	Hs
		719429 MERL_HUMAN (1-595): 1.12e-172: 504: 100.00		RIPK4_HUMAN (3-289): 4.7e-66: 222: 22.26
+	Hs
		719616 MERL_HUMAN (1-595): 1.12e-172: 504: 100.00		Q9H4D1_HUMAN (3-289): 1.34e-65: 220: 21.92
+	Hs
		166880 EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20		ANR28_HUMAN (135-290): 3.44e-36: 139: 19.50
+	Hs
		883686 FARP1_HUMAN (2-526): 5.38e-114: 366: 18.35		RIPK4_HUMAN (3-289): 4.7e-66: 222: 22.26
+	Hs
		1330900 FARP1_HUMAN (2-526): 5.38e-114: 366: 18.35		Q9H4D1_HUMAN (3-289): 1.34e-65: 220: 21.92
+	Hs
		883679 E41L3_HUMAN (14-484): 8.79e-113: 363: 21.04		RIPK4_HUMAN (3-289): 4.7e-66: 222: 22.26
+	Hs
		1330892 E41L3_HUMAN (14-484): 8.79e-113: 363: 21.04		Q9H4D1_HUMAN (3-289): 1.34e-65: 220: 21.92
+	Hs
		547272 EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20		KDIS_HUMAN (4-178): 2.86e-33: 131: 20.56
+	Hs
		547029 EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20		ANK3_HUMAN (173-291): 4e-31: 124: 13.12
+	Hs
		547010 EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20		ANK2_HUMAN (162-290): 8.92e-30: 121: 14.39
+	Hs
		257705 E41L5_HUMAN (2-595): 6.77e-134: 410: 18.38		ANR17_HUMAN (192-294): 2.61e-23: 101: 14.15
+	Hs
		1336475 E41LA_HUMAN (19-416): 3.96e-121: 375: 24.46		KDIS_HUMAN (4-178): 2.86e-33: 131: 20.56
+	Hs
		1219853 E41L5_HUMAN (2-595): 6.77e-134: 410: 18.38		ANKH1_HUMAN (192-294): 4.14e-20: 92.5: 14.15
+	Hs
		1021466 E41LA_HUMAN (19-416): 3.96e-121: 375: 24.46		ANK3_HUMAN (173-291): 4e-31: 124: 13.12
+	Hs
		640286 PTN3_HUMAN (3-433): 3.81e-115: 366: 22.52		KDIS_HUMAN (4-178): 2.86e-33: 131: 20.56
+	Hs
		1021479 FARP1_HUMAN (2-526): 5.38e-114: 366: 18.35		ANK3_HUMAN (173-291): 4e-31: 124: 13.12
+	Hs
		965179 FARP1_HUMAN (2-526): 5.38e-114: 366: 18.35		ANK2_HUMAN (162-290): 8.92e-30: 121: 14.39
+	Hs
		965178 E41L3_HUMAN (14-484): 8.79e-113: 363: 21.04		ANK2_HUMAN (162-290): 8.92e-30: 121: 14.39
+	Hs
		1377284 E41L3_HUMAN (14-484): 8.79e-113: 363: 21.04		ASB3_HUMAN (37-219): 1.2e-20: 93.6: 31.25
+	Hs
		640287 PTN3_HUMAN (3-433): 3.81e-115: 366: 22.52		ANR50_HUMAN (213-291): 1.39e-09: 60.9: 10.13