HitPredict

Interactor 1: MERL (P35240)
Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin)
Gene: NF2

Interactor 2: PALS2 (Q9NZW5)
Protein PALS2 (MAGUK p55 subfamily member 6) (Membrane protein, palmitoylated 6) (Veli-associated MAGUK 1) (VAM-1)
Gene: PALS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26549023
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 540
+	Hs
		719486 MERL_HUMAN (1-595): 1.12e-172: 504: 100.00		MPP2_HUMAN (1-540): 2.39e-179: 519: 66.31
+	Hs
		719540 MERL_HUMAN (1-595): 1.12e-172: 504: 100.00		PALS1_HUMAN (1-539): 7.94e-140: 421: 33.87
+	Mm
		250719 E41L2_MOUSE (10-519): 5.29e-114: 364: 20.68		PALS2_MOUSE (1-540): 0: 537: 95.49
+	Hs
		159150 EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20		CSKP_HUMAN (1-540): 9.97e-146: 444: 37.92
+	Hs
		547033 EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20		MPP3_HUMAN (1-539): 7.82e-135: 405: 32.42
+	Hs
		159272 E41L5_HUMAN (2-595): 6.77e-134: 410: 18.38		CSKP_HUMAN (1-540): 9.97e-146: 444: 37.92
+	Hs
		159142 EPB41_HUMAN (3-566): 9.71e-126: 392: 19.73		CSKP_HUMAN (1-540): 9.97e-146: 444: 37.92
+	Hs
		1232502 E41L5_HUMAN (2-595): 6.77e-134: 410: 18.38		PALS1_HUMAN (1-539): 7.94e-140: 421: 33.87
+	Hs
		159273 E41LA_HUMAN (19-416): 3.96e-121: 375: 24.46		CSKP_HUMAN (1-540): 9.97e-146: 444: 37.92
+	Hs
		1232503 E41LA_HUMAN (19-416): 3.96e-121: 375: 24.46		PALS1_HUMAN (1-539): 7.94e-140: 421: 33.87
+	Hs
		663981 PTN4_HUMAN (1-515): 8.77e-124: 388: 21.09		MPP7_HUMAN (1-540): 2.61e-135: 406: 34.74
+	Hs
		1232517 E41L3_HUMAN (14-484): 8.79e-113: 363: 21.04		PALS1_HUMAN (1-539): 7.94e-140: 421: 33.87
+	Hs
		1132894 E41LA_HUMAN (19-416): 3.96e-121: 375: 24.46		MPP7_HUMAN (1-540): 2.61e-135: 406: 34.74
+	Ce
		184973 O17905_CAEEL (1-592): 3.24e-112: 362: 14.49		LIN2_CAEEL (3-540): 1.81e-134: 415: 34.32
+	Hs
		547030 EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20		DLG1_HUMAN (7-214): 3.38e-14: 77.6: 14.91
+	Hs
		505627 EPB41_HUMAN (3-566): 9.71e-126: 392: 19.73		DLG1_HUMAN (7-214): 3.38e-14: 77.6: 14.91
+	Hs
		1021565 E41LA_HUMAN (19-416): 3.96e-121: 375: 24.46		DLG1_HUMAN (7-214): 3.38e-14: 77.6: 14.91
+	Mm
		1143556 E41L3_MOUSE (14-544): 5.06e-116: 368: 20.89		DLG4_MOUSE (88-214): 2.28e-14: 78: 16.42
+	Mm
		1143533 E41LB_MOUSE (1-455): 9.3e-117: 358: 20.30		DLG4_MOUSE (88-214): 2.28e-14: 78: 16.42