HitPredict

Interactor 1: MERL (P35240)
Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin)
Gene: NF2

Interactor 2: AP3M1 (Q9Y2T2)
AP-3 complex subunit mu-1 (AP-3 adaptor complex mu3A subunit) (Adaptor-related protein complex 3 subunit mu-1) (Mu-adaptin 3A) (Mu3A-adaptin)
Gene: AP3M1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 418
+	Hs
		1336374 E41L5_HUMAN (2-595): 6.77e-134: 410: 18.38		AP3M1_HUMAN (1-418): 2.88e-162: 464: 100.00
+	Hs
		1331063 E41L1_HUMAN (1-535): 3.42e-120: 378: 21.61		AP3M1_HUMAN (1-418): 2.88e-162: 464: 100.00
+	Hs
		1336479 E41LA_HUMAN (19-416): 3.96e-121: 375: 24.46		AP3M1_HUMAN (1-418): 2.88e-162: 464: 100.00
+	Hs
		1377282 E41L3_HUMAN (14-484): 8.79e-113: 363: 21.04		AP3M1_HUMAN (1-418): 2.88e-162: 464: 100.00
+	Hs
		864056 E41L3_HUMAN (14-484): 8.79e-113: 363: 21.04		AP3M2_HUMAN (1-418): 1.44e-152: 439: 84.21