HitPredict

Interactor 1: RADI (P35241)
Radixin
Gene: RDX

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0008360 - regulation of cell shape GO:0008361 - regulation of cell size GO:0030027 - lamellipodium and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 583 Hs			1 192
+	Hs
		547002 EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		545234 RADI_HUMAN (1-583): 3.49e-166: 487: 100.00		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		546995 EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		640084 MOES_HUMAN (1-583): 2.8e-161: 474: 80.96		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		719441 MERL_HUMAN (2-583): 1.72e-151: 450: 45.30		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		564429 MERL_HUMAN (2-583): 1.72e-151: 450: 45.30		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		545233 MERL_HUMAN (2-583): 1.72e-151: 450: 45.30		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		719617 MERL_HUMAN (2-583): 1.72e-151: 450: 45.30		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		719431 MERL_HUMAN (2-583): 1.72e-151: 450: 45.30		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		719446 MERL_HUMAN (2-583): 1.72e-151: 450: 45.30		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		719433 MERL_HUMAN (2-583): 1.72e-151: 450: 45.30		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		925637 E41L5_HUMAN (5-567): 7.64e-125: 385: 19.55		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		564694 E41L5_HUMAN (5-567): 7.64e-125: 385: 19.55		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		545630 E41L5_HUMAN (5-567): 7.64e-125: 385: 19.55		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		505620 EPB41_HUMAN (3-553): 1.19e-125: 392: 20.48		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		892609 E41L5_HUMAN (5-567): 7.64e-125: 385: 19.55		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		951359 E41L5_HUMAN (5-567): 7.64e-125: 385: 19.55		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		894461 E41L5_HUMAN (5-567): 7.64e-125: 385: 19.55		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		900931 E41L5_HUMAN (5-567): 7.64e-125: 385: 19.55		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		436519 E41L5_HUMAN (5-567): 7.64e-125: 385: 19.55		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45