HitPredict

Interactor 1: RFA3 (P35244)
Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3)
Gene: RPA3

Interactor 2: CHD1L (Q86WJ1)
Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.-) (Amplified in liver cancer protein 1)
Gene: CHD1L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	37827155, 19666485
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0006281 - DNA repair GO:0035861 - site of double-strand break
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 121 Hs			1 897
+	Hs
		721504 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		CHD8_HUMAN (1-856): 0: 643: 27.69
+	Hs
		229324 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		SMCA5_HUMAN (9-786): 0: 603: 32.60
+	Hs
		720483 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		CHD4_HUMAN (18-775): 0: 584: 32.19
+	Hs
		720008 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		SMCA4_HUMAN (3-782): 0: 567: 29.03
+	Hs
		151384 RFA3_HUMAN (1-121): 2.63e-81: 235: 100.00		CHD1_HUMAN (40-526): 5.8e-112: 379: 45.51