HitPredict

Interactor 1: B3KSH4 (B3KSH4)
Huntingtin interacting protein 2, isoform CRA_a (cDNA FLJ36214 fis, clone THYMU2000672, highly similar to Ubiquitin-conjugating enzyme E2-25 kDa)
Gene: HIP2

Interactor 2: R144A (P50876)
E3 ubiquitin-protein ligase RNF144A (EC 2.3.2.31) (RING finger protein 144A) (UbcM4-interacting protein 4) (Ubiquitin-conjugating enzyme 7-interacting protein 4)
Gene: RNF144A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19549727
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	IBR~UQ_con
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 97 Hs			1 292
+	Hs
		842098 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		R144A_HUMAN (1-292): 5.59e-97: 288: 100.00
+	Hs
		842104 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		R144A_HUMAN (1-292): 5.59e-97: 288: 100.00
+	Hs
		919876 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RN19A_HUMAN (16-276): 5.96e-75: 246: 25.00
+	Hs
		919757 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RN19B_HUMAN (13-276): 3.98e-73: 240: 25.54
+	Hs
		895819 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		RN19B_HUMAN (13-276): 3.98e-73: 240: 25.54
+	Hs
		312553 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		ARI2_HUMAN (2-231): 1.5e-64: 211: 25.53
+	Hs
		895968 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		ARI1_HUMAN (14-229): 1.58e-64: 213: 27.35
+	Hs
		312528 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		ARI2_HUMAN (2-231): 1.5e-64: 211: 25.53
+	Hs
		312679 UB2D4_HUMAN (1-51): 1.33e-28: 101: 39.22		ARI2_HUMAN (2-231): 1.5e-64: 211: 25.53
+	Hs
		919891 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RNF14_HUMAN (14-239): 1.82e-59: 198: 22.93
+	Hs
		895938 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		RNF14_HUMAN (14-239): 1.82e-59: 198: 22.93
+	Dm
		639397 UBCD1_DROME (1-51): 1.57e-29: 104: 39.22		LUBEL_DROME (19-225): 2.33e-55: 194: 22.22
+	Hs
		896351 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		RNF31_HUMAN (19-218): 8.15e-50: 178: 23.04
+	Hs
		919819 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RNF31_HUMAN (19-218): 8.15e-50: 178: 23.04
+	Hs
		895873 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		RNF31_HUMAN (19-218): 8.15e-50: 178: 23.04
+	Hs
		1290106 UB2D4_HUMAN (1-51): 1.33e-28: 101: 39.22		RNF31_HUMAN (19-218): 8.15e-50: 178: 23.04
+	Mm
		895978 UB2D3_MOUSE (1-51): 6.77e-29: 102: 35.29		RNF31_MOUSE (19-218): 2.3e-49: 177: 23.26
+	Hs
		919878 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RN216_HUMAN (17-219): 3.83e-12: 68.6: 27.54
+	Hs
		895928 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		RN216_HUMAN (17-219): 3.83e-12: 68.6: 27.54
+	Hs
		1347205 UB2D4_HUMAN (1-51): 1.33e-28: 101: 39.22		RN216_HUMAN (17-219): 3.83e-12: 68.6: 27.54