HitPredict

Interactor 1: B3KSH4 (B3KSH4)
Huntingtin interacting protein 2, isoform CRA_a (cDNA FLJ36214 fis, clone THYMU2000672, highly similar to Ubiquitin-conjugating enzyme E2-25 kDa)
Gene: HIP2

Interactor 2: RN138 (Q8WVD3)
E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (Nemo-like kinase-associated RING finger protein) (NLK-associated RING finger protein) (hNARF) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138)
Gene: RNF138

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19549727
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 97 Hs			1 245
+	Hs
		896344 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		RN138_HUMAN (1-245): 6.92e-57: 183: 100.00
+	Hs
		896346 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		RN166_HUMAN (5-244): 4.23e-40: 140: 29.58
+	Hs
		896402 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		RN114_HUMAN (16-241): 4.34e-36: 129: 30.53
+	Hs
		72172 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		RN114_HUMAN (16-241): 4.34e-36: 129: 30.53
+	Hs
		896352 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		RN125_HUMAN (2-243): 3.21e-33: 122: 26.86
+	Hs
		72151 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		RN125_HUMAN (2-243): 3.21e-33: 122: 26.86
+	Hs
		896348 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		TRI43_HUMAN (6-245): 1.85e-29: 116: 15.29
+	Hs
		896381 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		TRI39_HUMAN (9-186): 1.44e-28: 114: 17.22
+	Hs
		72149 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		TRI43_HUMAN (6-245): 1.85e-29: 116: 15.29
+	Hs
		896370 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		TRIM5_HUMAN (5-160): 2.04e-28: 113: 14.91
+	Hs
		896360 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		RING2_HUMAN (2-188): 8.11e-29: 112: 18.72
+	Hs
		896376 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		RNF41_HUMAN (1-158): 7.35e-29: 112: 20.96
+	Hs
		72168 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		TRI39_HUMAN (9-186): 1.44e-28: 114: 17.22
+	Hs
		72161 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		TRIM5_HUMAN (5-160): 2.04e-28: 113: 14.91
+	Hs
		72155 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		RING2_HUMAN (2-188): 8.11e-29: 112: 18.72
+	Hs
		72165 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		RNF41_HUMAN (1-158): 7.35e-29: 112: 20.96
+	Hs
		896369 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		TRI31_HUMAN (6-156): 1.18e-25: 105: 17.65
+	Hs
		72160 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		TRI31_HUMAN (6-156): 1.18e-25: 105: 17.65
+	Hs
		896302 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		RING1_HUMAN (2-74): 3.94e-21: 92.7: 27.40
+	Hs
		72138 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		RING1_HUMAN (2-74): 3.94e-21: 92.7: 27.40