HitPredict

Interactor 1: T2FA (P35269)
General transcription factor IIF subunit 1 (General transcription factor IIF 74 kDa subunit) (Transcription initiation factor IIF subunit alpha) (TFIIF-alpha) (Transcription initiation factor RAP74)
Gene: GTF2F1

Interactor 2: CTDP1 (Q9Y5B0)
RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase)
Gene: CTDP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.882

The method score is based on:

Property Details
Experiments 12591939, 12732728, 9765293
Identification Methods affinity chromatography technology, x-ray crystallography, two hybrid, pull down, nuclear magnetic resonance
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains FCP1_C~TFIIF_alpha
Common GO terms GO:0001096 - TFIIF-class transcription factor complex binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006368 - transcription elongation by RNA polymerase II
GO:0032991 - protein-containing complex
and 1 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 517
Hs

1 961
+ Hs
+ Sc
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024