HitPredict

Interactor 1: ADA1A (P35348)
Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c)
Gene: ADRA1A

Interactor 2: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	28298427
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043410 - positive regulation of MAPK cascade
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 466 Hs			1 236
+	Hs
		428997 ADRB2_HUMAN (4-376): 7.56e-81: 258: 29.92		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		887838 5HT4R_HUMAN (1-418): 2.72e-75: 243: 26.79		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		428955 ADRB2_HUMAN (4-376): 7.56e-81: 258: 29.92		TSN7_HUMAN (1-234): 7.1e-56: 180: 22.31
+	Hs
		428918 ADRB2_HUMAN (4-376): 7.56e-81: 258: 29.92		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		783912 5HT4R_HUMAN (1-418): 2.72e-75: 243: 26.79		TSN7_HUMAN (1-234): 7.1e-56: 180: 22.31
+	Hs
		208446 OX2R_HUMAN (21-402): 9.71e-76: 245: 20.10		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		326031 NK3R_HUMAN (1-425): 7.31e-67: 223: 17.47		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		537264 DRD2_HUMAN (248-341): 2.92e-14: 76.6: 42.27		TSN7_HUMAN (1-234): 7.1e-56: 180: 22.31
+	Hs
		237781 DRD2_HUMAN (248-341): 2.92e-14: 76.6: 42.27		TSN3_HUMAN (4-236): 1.19e-43: 149: 18.88