Interactor 1: PGH2 (P35354)
Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2)
Gene: PTGS2

Interactor 2: PGH2 (P35354)
Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2)
Gene: PTGS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.896

The method score is based on:

Property Details
Experiments 27226593, 23955344, 16606823, 21467029
Identification Methods x-ray crystallography, pull down, anti tag coimmunoprecipitation
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains An_peroxidase~An_peroxidase
Common GO terms GO:0001516 - prostaglandin biosynthetic process
GO:0001525 - angiogenesis
GO:0004601 - peroxidase activity
GO:0004666 - prostaglandin-endoperoxide synthase activity
GO:0005637 - nuclear inner membrane
and 69 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 604
Hs

1 604
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024