HitPredict

Interactor 1: OPRM (P35372)
Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)
Gene: OPRM1

Interactor 2: VAPA (Q9P0L0)
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)
Gene: VAPA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.651

Property	Details
Experiments	23840749, 28298427
Identification Methods	two hybrid, affinity chromatography technology, ubiquitin reconstruction, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 400 Hs			1 249
+	Mm
		792164 OPRM_MOUSE (1-400): 6.24e-106: 319: 94.00		VAPA_MOUSE (1-249): 2.59e-99: 291: 97.19
+	Hs
		781045 OPRK_HUMAN (13-389): 2.58e-84: 263: 55.38		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		781035 OPRD_HUMAN (22-383): 7.64e-84: 262: 60.33		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		429142 ADRB2_HUMAN (66-397): 9.96e-79: 250: 21.11		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		1281150 KISSR_HUMAN (20-353): 7.42e-37: 140: 30.88		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		895679 CXCR4_HUMAN (70-346): 1.36e-78: 247: 27.82		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34
+	Hs
		626558 FPR2_HUMAN (71-346): 4.5e-36: 136: 32.08		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34