HitPredict

Interactor 1: GRM7 (P35400)
Metabotropic glutamate receptor 7 (mGluR7)
Gene: GRM7

Interactor 2: PICK1 (Q9EP80)
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)
Gene: PICK1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.620

Property	Details
Experiments	11007882, 11891216
Identification Methods	anti bait coimmunoprecipitation, pull down, two hybrid array, anti tag coimmunoprecipitation, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030425 - dendrite GO:0032991 - protein-containing complex GO:0042734 - presynaptic membrane GO:0098978 - glutamatergic synapse
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 915 Rn			1 416
+	Hs
		1059608 GRM7_HUMAN (1-915): 0: 1002: 99.34		PICK1_HUMAN (1-416): 0: 582: 97.12
+	Rn
		680331 GRM3_RAT (8-896): 0: 810: 42.75		PICK1_RAT (1-416): 0: 604: 100.00
+	Rn
		680328 GRM2_RAT (31-896): 0: 801: 43.38		PICK1_RAT (1-416): 0: 604: 100.00
+	Hs
		1059611 GRM3_HUMAN (8-896): 0: 809: 43.41		PICK1_HUMAN (1-416): 0: 582: 97.12
+	Rn
		786686 GRIK2_RAT (9-711): 6.47e-112: 367: 12.97		PICK1_RAT (1-416): 0: 604: 100.00
+	Hs
		761212 GRIK1_HUMAN (12-711): 3.56e-114: 373: 13.49		PICK1_HUMAN (1-416): 0: 582: 97.12
+	Hs
		1022367 GRIK2_HUMAN (7-711): 1.09e-113: 371: 12.94		PICK1_HUMAN (1-416): 0: 582: 97.12
+	Rn
		611607 GRIK1_RAT (12-653): 1.69e-94: 321: 14.54		PICK1_RAT (1-416): 0: 604: 100.00