HitPredict

Interactor 1: NMDZ1 (P35438)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: Grin1

Interactor 2: ZO1 (P39447)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: Tjp1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	10862698
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005516 - calmodulin binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 938 Mm			1 1745
+	Rn
		677765 NMDZ1_RAT (1-938): 0: 920: 99.79		DLG4_RAT (1-112): 4.83e-27: 121: 29.92
+	Mm
		723586 NMDZ1_MOUSE (1-938): 0: 920: 100.00		DLG4_MOUSE (1-112): 6.11e-27: 121: 29.92
+	Hs
		942329 NMDZ1_HUMAN (1-938): 0: 914: 99.04		DLG4_HUMAN (1-112): 6.66e-27: 121: 29.92
+	Mm
		57144 A2AI21_MOUSE (1-938): 0: 910: 97.71		DLG4_MOUSE (1-112): 6.11e-27: 121: 29.92
+	Mm
		723606 NMDZ1_MOUSE (1-938): 0: 920: 100.00		DLG2_MOUSE (349-508): 1.59e-15: 84.6: 19.64
+	Mm
		723600 NMDZ1_MOUSE (1-938): 0: 920: 100.00		DLG1_MOUSE (281-512): 9.78e-15: 82.3: 16.25
+	Hs
		984257 NMDZ1_HUMAN (1-938): 0: 914: 99.04		DLG1_HUMAN (264-512): 3.5e-15: 83.4: 15.95
+	Mm
		723568 NMDZ1_MOUSE (1-938): 0: 920: 100.00		DLG3_MOUSE (288-507): 1.64e-11: 71.5: 18.33
+	Rn
		723628 NMDZ1_RAT (1-938): 0: 920: 99.79		DLG3_RAT (288-507): 1.98e-11: 71.1: 18.33
+	Hs
		1022366 GRIK2_HUMAN (10-900): 0: 724: 22.32		DLG3_HUMAN (16-265): 4.16e-47: 185: 20.39
+	Dm
		677690 NMDA1_DROME (20-923): 0: 688: 44.70		DLG1_DROME (2-318): 9.35e-40: 163: 18.18
+	Hs
		942335 GRIK2_HUMAN (10-900): 0: 724: 22.32		DLG4_HUMAN (1-112): 6.66e-27: 121: 29.92
+	Rn
		677766 GRIK2_RAT (3-900): 0: 723: 22.26		DLG4_RAT (1-112): 4.83e-27: 121: 29.92
+	Mm
		761217 GRIK2_MOUSE (3-900): 0: 723: 22.26		DLG4_MOUSE (1-112): 6.11e-27: 121: 29.92
+	Hs
		761199 GRIK1_HUMAN (8-869): 0: 709: 23.41		DLG4_HUMAN (1-112): 6.66e-27: 121: 29.92
+	Hs
		1021483 GRIK2_HUMAN (10-900): 0: 724: 22.32		DLG1_HUMAN (264-512): 3.5e-15: 83.4: 15.95
+	Rn
		585138 GRIA1_RAT (5-904): 0: 672: 21.64		DLG4_RAT (1-112): 4.83e-27: 121: 29.92
+	Hs
		786696 GRIA1_HUMAN (5-904): 0: 680: 21.77		DLG1_HUMAN (264-512): 3.5e-15: 83.4: 15.95
+	Rn
		585151 GRIA1_RAT (5-904): 0: 672: 21.64		DLG1_RAT (5-111): 4.72e-14: 80: 29.36
+	Mm
		620881 GRIA1_MOUSE (5-904): 0: 669: 21.75		DLG3_MOUSE (288-507): 1.64e-11: 71.5: 18.33