HitPredict

Interactor 1: NMDZ1 (P35438)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: Grin1

Interactor 2: NMDE2 (Q01097)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B)
Gene: Grin2b

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 36417873, 10862698, 16554481, 14645471, 9003035, 15663482, 19243221, 32033586, 34646371, 20141836
Identification Methods proximity labelling technology, affinity chromatography technology, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan~SBP_bac_3, Lig_chan-Glu_bd~Lig_chan-Glu_bd, Lig_chan-Glu_bd~SBP_bac_3, SBP_bac_3~SBP_bac_3
Common GO terms GO:0001964 - startle response
GO:0001967 - suckling behavior
GO:0004970 - glutamate-gated receptor activity
GO:0004972 - NMDA glutamate receptor activity
GO:0005102 - signaling receptor binding
and 50 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 938
Mm

1 1482
+ Rn
+ Hs
+ Xl
+ Mm
+ Rn
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Rn
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024