HitPredict

Interactor 1: NMDZ1 (P35438)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: Grin1

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.757

The method score is based on:

Property Details
Experiments 27507650, 28671696, 9647694, 36417873, 36604605, 16554481, 10862698, 15663482, 19240213, 19243221, 19455133, 16601687
Identification Methods affinity chromatography technology, two hybrid, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005102 - signaling receptor binding
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0007268 - chemical synaptic transmission
and 21 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 938
Mm

1 724
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Last updated: 15 Jul 2024