HitPredict

Interactor 1: NMDZ1 (P35438)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: Grin1

Interactor 2: DAPK1 (Q80YE7)
Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)
Gene: DAPK1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20141836
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005516 - calmodulin binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0043065 - positive regulation of apoptotic process and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 938 Mm			1 1442
+	Mm
		963749 NMDE2_MOUSE (4-938): 0: 628: 23.86		DAPK1_MOUSE (1-1442): 0: 2004: 100.00
+	Mm
		515217 NMDZ1_MOUSE (1-938): 0: 920: 100.00		KCC2A_MOUSE (1-383): 1.5e-117: 379: 29.17
+	Hs
		984288 NMDZ1_HUMAN (1-938): 0: 914: 99.04		KCC2A_HUMAN (1-383): 1.64e-117: 378: 29.17
+	Mm
		57832 NMDZ1_MOUSE (1-938): 0: 920: 100.00		KALRN_MOUSE (2-312): 1.28e-60: 232: 38.26
+	Hs
		786716 GRIA1_HUMAN (5-904): 0: 680: 21.77		KCC2A_HUMAN (1-383): 1.64e-117: 378: 29.17
+	Rn
		506693 GRIA1_RAT (5-904): 0: 672: 21.64		KCC2A_RAT (1-383): 1.5e-117: 379: 29.17
+	Hs
		816227 GRIA4_HUMAN (7-888): 0: 659: 21.72		KCC2A_HUMAN (1-383): 1.64e-117: 378: 29.17
+	Hs
		984274 NMDZ1_HUMAN (1-938): 0: 914: 99.04		ANKK1_HUMAN (641-964): 1.88e-22: 106: 12.43
+	Hs
		1028155 NMDE2_HUMAN (4-938): 0: 634: 24.07		KCC2A_HUMAN (1-383): 1.64e-117: 378: 29.17
+	Rn
		550161 NMDE2_RAT (4-938): 0: 632: 23.96		KCC2D_RAT (8-347): 1.82e-117: 380: 31.97
+	Rn
		506719 NMDE2_RAT (4-938): 0: 632: 23.96		KCC2A_RAT (1-383): 1.5e-117: 379: 29.17
+	Mm
		515226 NMDE2_MOUSE (4-938): 0: 628: 23.86		KCC2A_MOUSE (1-383): 1.5e-117: 379: 29.17
+	Hs
		224704 GRIK1_HUMAN (8-869): 0: 709: 23.41		KALRN_HUMAN (2-312): 7.57e-61: 233: 38.59
+	Rn
		585146 GRIA1_RAT (5-904): 0: 672: 21.64		KALRN_RAT (2-312): 1.19e-60: 232: 38.26
+	Mm
		57882 GRIA3_MOUSE (2-859): 0: 637: 21.69		KALRN_MOUSE (2-312): 1.28e-60: 232: 38.26
+	Rn
		957072 NMDE2_RAT (4-938): 0: 632: 23.96		KALRN_RAT (2-312): 1.19e-60: 232: 38.26
+	Mm
		57819 G3X9V4_MOUSE (4-938): 0: 629: 23.86		KALRN_MOUSE (2-312): 1.28e-60: 232: 38.26
+	Mm
		57829 GRIA2_MOUSE (3-856): 0: 628: 21.55		KALRN_MOUSE (2-312): 1.28e-60: 232: 38.26
+	Mm
		57838 NMDE2_MOUSE (4-938): 0: 628: 23.86		KALRN_MOUSE (2-312): 1.28e-60: 232: 38.26
+	Mm
		57814 F2Z488_MOUSE (2-806): 0: 595: 21.73		KALRN_MOUSE (2-312): 1.28e-60: 232: 38.26