HitPredict

Interactor 1: NMDZ1 (P35438)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: Grin1

Interactor 2: DLGP1 (Q9D415)
Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1)
Gene: Dlgap1

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	27507650, 28671696, 10862698
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007268 - chemical synaptic transmission GO:0014069 - postsynaptic density GO:0044877 - protein-containing complex binding GO:0045202 - synapse GO:0045211 - postsynaptic membrane and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 938 Mm			1 992
+	Mm
		620907 GRIA1_MOUSE (5-904): 0: 669: 21.75		DLGP1_MOUSE (1-992): 0: 1344: 100.00
+	Mm
		1322034 GRIA3_MOUSE (2-859): 0: 637: 21.69		DLGP1_MOUSE (1-992): 0: 1344: 100.00
+	Mm
		621034 GRIA2_MOUSE (3-856): 0: 628: 21.55		DLGP1_MOUSE (1-992): 0: 1344: 100.00
+	Mm
		963772 NMDE2_MOUSE (4-938): 0: 628: 23.86		DLGP1_MOUSE (1-992): 0: 1344: 100.00
+	Hs
		145946 NMDE1_HUMAN (1-923): 0: 623: 24.11		DLGP1_HUMAN (1-992): 0: 1324: 94.46
+	Mm
		723542 NMDE1_MOUSE (1-923): 0: 593: 24.22		DLGP1_MOUSE (1-992): 0: 1344: 100.00
+	Mm
		620992 GRIA2_MOUSE (3-856): 0: 628: 21.55		DLGP2_MOUSE (1-992): 0: 1079: 50.82
+	Mm
		69912 GRIA2_MOUSE (3-856): 0: 628: 21.55		DLGP4_MOUSE (1-992): 0: 1056: 45.88
+	Mm
		620896 GRIA1_MOUSE (5-904): 0: 669: 21.75		DLGP3_MOUSE (1-992): 0: 978: 38.13
+	Mm
		620975 GRIA2_MOUSE (3-856): 0: 628: 21.55		DLGP3_MOUSE (1-992): 0: 978: 38.13
+	Mm
		963737 NMDE2_MOUSE (4-938): 0: 628: 23.86		DLGP3_MOUSE (1-992): 0: 978: 38.13
+	Mm
		976162 NMDE4_MOUSE (395-829): 2.51e-64: 238: 30.96		DLGP1_MOUSE (1-992): 0: 1344: 100.00