Interactor 1: NMDZ1 (P35439)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: Grin1

Interactor 2: NMDE2 (Q00960)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B)
Gene: Grin2b

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.962

The method score is based on:

Property Details
Experiments 17670980, 23221411, 24876489, 21677647, 27135925, 19243221, 8780649
Identification Methods affinity chromatography technology, cross-linking study, molecular sieving, x-ray crystallography, 3D electron microscopy, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan~SBP_bac_3, Lig_chan-Glu_bd~Lig_chan-Glu_bd, Lig_chan-Glu_bd~SBP_bac_3, SBP_bac_3~SBP_bac_3
Common GO terms GO:0001666 - response to hypoxia
GO:0001964 - startle response
GO:0001967 - suckling behavior
GO:0001975 - response to amphetamine
GO:0004970 - glutamate-gated receptor activity
and 63 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 938
Rn

1 1482
+ Mm
+ Hs
+ Xl
+ Mm
+ Rn
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Rn
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Rn
+ Hs
+ Rn
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024