HitPredict

Interactor 1: NMDZ1 (P35439)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: Grin1

Interactor 2: NHRF3 (Q9JJ40)
Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3) (C-terminal-linking and modulating protein) (Dietary Pi-regulated RNA-1) (Diphor-1) (Na(+)/H(+) exchanger regulatory factor 3) (Na/Pi cotransporter C-terminal-associated protein 1) (NaPi-Cap1) (PDZ domain-containing protein 1) (Sodium-hydrogen exchanger regulatory factor 3)
Gene: Pdzk1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16054660
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005102 - signaling receptor binding GO:0005886 - plasma membrane GO:0044877 - protein-containing complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 938 Rn			1 523
+	Hs
		984257 NMDZ1_HUMAN (1-938): 0: 926: 99.25		DLG1_HUMAN (3-417): 7.3e-46: 174: 17.53
+	Rn
		723628 NMDZ1_RAT (1-938): 0: 932: 100.00		DLG3_RAT (194-514): 1.38e-23: 107: 16.12
+	Mm
		723568 NMDZ1_MOUSE (1-938): 0: 932: 99.79		DLG3_MOUSE (142-514): 1.59e-23: 106: 14.47
+	Hs
		984275 NMDZ1_HUMAN (1-938): 0: 926: 99.25		LNX1_HUMAN (2-214): 9.99e-23: 104: 17.41
+	Mm
		723606 NMDZ1_MOUSE (1-938): 0: 932: 99.79		DLG2_MOUSE (297-459): 3.51e-14: 77.5: 17.65
+	Rn
		677765 NMDZ1_RAT (1-938): 0: 932: 100.00		DLG4_RAT (316-462): 7.3e-14: 76.3: 16.88
+	Mm
		723586 NMDZ1_MOUSE (1-938): 0: 932: 99.79		DLG4_MOUSE (316-462): 7.9e-14: 76.3: 16.88
+	Mm
		723600 NMDZ1_MOUSE (1-938): 0: 932: 99.79		DLG1_MOUSE (218-462): 2.23e-13: 75.2: 14.39
+	Hs
		942329 NMDZ1_HUMAN (1-938): 0: 926: 99.25		DLG4_HUMAN (316-462): 7.83e-14: 76.3: 16.88
+	Mm
		57144 A2AI21_MOUSE (1-938): 0: 923: 97.39		DLG4_MOUSE (316-462): 7.9e-14: 76.3: 16.88
+	Hs
		1021483 GRIK2_HUMAN (10-900): 0: 722: 22.59		DLG1_HUMAN (3-417): 7.3e-46: 174: 17.53
+	Hs
		786696 GRIA1_HUMAN (5-904): 0: 696: 21.67		DLG1_HUMAN (3-417): 7.3e-46: 174: 17.53
+	Hs
		1022366 GRIK2_HUMAN (10-900): 0: 722: 22.59		DLG3_HUMAN (218-514): 2.86e-22: 102: 17.69
+	Rn
		677766 GRIK2_RAT (3-900): 0: 722: 22.53		DLG4_RAT (316-462): 7.3e-14: 76.3: 16.88
+	Hs
		942335 GRIK2_HUMAN (10-900): 0: 722: 22.59		DLG4_HUMAN (316-462): 7.83e-14: 76.3: 16.88
+	Mm
		761217 GRIK2_MOUSE (3-900): 0: 721: 22.53		DLG4_MOUSE (316-462): 7.9e-14: 76.3: 16.88
+	Mm
		620881 GRIA1_MOUSE (6-904): 0: 685: 21.67		DLG3_MOUSE (142-514): 1.59e-23: 106: 14.47
+	Hs
		761199 GRIK1_HUMAN (8-869): 0: 707: 23.47		DLG4_HUMAN (316-462): 7.83e-14: 76.3: 16.88
+	Rn
		585151 GRIA1_RAT (6-904): 0: 688: 21.56		DLG1_RAT (253-468): 4.12e-14: 77.4: 16.38
+	Rn
		585138 GRIA1_RAT (6-904): 0: 688: 21.56		DLG4_RAT (316-462): 7.3e-14: 76.3: 16.88