HitPredict

Interactor 1: HXD13 (P35453)
Homeobox protein Hox-D13 (Homeobox protein Hox-4I)
Gene: HOXD13

Interactor 2: FOXB1 (Q99853)
Forkhead box protein B1 (Transcription factor FKH-5)
Gene: FOXB1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25609649
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0006357 - regulation of transcription by RNA polymerase II GO:1990837 - sequence-specific double-stranded DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 343 Hs			1 325
+	Hs
		723676 HXD13_HUMAN (1-343): 2.97e-65: 211: 100.00		FOXG1_HUMAN (11-313): 9.81e-53: 182: 25.87
+	Hs
		723677 HXD13_HUMAN (1-343): 2.97e-65: 211: 100.00		FOXA1_HUMAN (3-315): 3.38e-52: 180: 30.35
+	Hs
		723686 HXD13_HUMAN (1-343): 2.97e-65: 211: 100.00		FOXK2_HUMAN (5-325): 6.1e-50: 177: 23.46
+	Hs
		723713 HXD13_HUMAN (1-343): 2.97e-65: 211: 100.00		FOXQ1_HUMAN (5-181): 1.14e-51: 177: 33.15
+	Hs
		723698 HXD13_HUMAN (1-343): 2.97e-65: 211: 100.00		FOXI2_HUMAN (10-223): 1.6e-50: 172: 35.65
+	Hs
		723719 HXD13_HUMAN (1-343): 2.97e-65: 211: 100.00		FOXD3_HUMAN (4-216): 1.38e-47: 168: 41.32
+	Hs
		723692 HXD13_HUMAN (1-343): 2.97e-65: 211: 100.00		FOXC1_HUMAN (4-323): 2.51e-46: 166: 27.60
+	Hs
		723678 HXD13_HUMAN (1-343): 2.97e-65: 211: 100.00		FOXA3_HUMAN (1-212): 8.93e-47: 163: 42.52
+	Hs
		208897 HXD13_HUMAN (1-343): 2.97e-65: 211: 100.00		FOXS1_HUMAN (1-244): 1.39e-46: 162: 34.43
+	Hs
		723718 HXD13_HUMAN (1-343): 2.97e-65: 211: 100.00		FOXJ2_HUMAN (9-316): 7.31e-44: 160: 22.36
+	Hs
		723709 HXD13_HUMAN (1-343): 2.97e-65: 211: 100.00		FOXC2_HUMAN (8-324): 3.24e-44: 159: 29.34
+	Hs
		723724 HXD13_HUMAN (1-343): 2.97e-65: 211: 100.00		FOXA2_HUMAN (2-277): 8.71e-44: 157: 34.75
+	Hs
		723691 HXD13_HUMAN (1-343): 2.97e-65: 211: 100.00		FOXF1_HUMAN (9-297): 6.02e-44: 156: 26.69
+	Hs
		126436 HXD13_HUMAN (1-343): 2.97e-65: 211: 100.00		FOXE1_HUMAN (13-105): 5.62e-26: 107: 65.59
+	Hs
		877630 HXB13_HUMAN (67-343): 1.34e-36: 135: 36.17		FOXG1_HUMAN (11-313): 9.81e-53: 182: 25.87
+	Hs
		877884 ALX4_HUMAN (55-336): 1.4e-35: 135: 17.31		FOXA1_HUMAN (3-315): 3.38e-52: 180: 30.35
+	Hs
		878008 ALX4_HUMAN (55-336): 1.4e-35: 135: 17.31		FOXA3_HUMAN (1-212): 8.93e-47: 163: 42.52
+	Hs
		208928 HXB13_HUMAN (67-343): 1.34e-36: 135: 36.17		FOXS1_HUMAN (1-244): 1.39e-46: 162: 34.43
+	Hs
		126471 HXB13_HUMAN (67-343): 1.34e-36: 135: 36.17		FOXE1_HUMAN (13-105): 5.62e-26: 107: 65.59
+	Hs
		126476 ALX4_HUMAN (55-336): 1.4e-35: 135: 17.31		FOXE1_HUMAN (13-105): 5.62e-26: 107: 65.59