Interactor 1: ODPA (P35486)
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I)
Gene: Pdha1

Interactor 2: ODPB (Q9D051)
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHE1-B) (EC 1.2.4.1)
Gene: Pdhb

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 29128334
Identification Methods cross-linking study
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains E1_dh~Transket_pyr, E1_dh~Transketolase_C
Common GO terms GO:0004739 - pyruvate dehydrogenase (acetyl-transferring) activity
GO:0005739 - mitochondrion
GO:0006006 - glucose metabolic process
GO:0006086 - acetyl-CoA biosynthetic process from pyruvate
GO:0006099 - tricarboxylic acid cycle
and 3 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 390
Mm

1 359
+ Hs
+ Hs
+ Dm
+ Dm
+ At
+ Sc
+ At
+ Ce
+ Hs
+ Sc
+ Ce
+ Ce
+ Pp
+ Gs
+ Tt
+ Mp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024