HitPredict

Interactor 1: SCN1A (P35498)
Sodium channel protein type 1 subunit alpha (Sodium channel protein brain I subunit alpha) (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1)
Gene: SCN1A

Interactor 2: FGF12 (P61328)
Fibroblast growth factor 12 (FGF-12) (Fibroblast growth factor homologous factor 1) (FHF-1) (Myocyte-activating factor)
Gene: FGF12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	22705208
Identification Methods	isothermal titration calorimetry
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0086002 - cardiac muscle cell action potential involved in contraction
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2009 Hs			1 243
+	Hs
		1272762 SCN2A_HUMAN (1-2009): 0: 2064: 85.20		FGF13_HUMAN (1-243): 4.47e-105: 305: 65.74
+	Hs
		899630 SCN5A_HUMAN (3-2003): 0: 1865: 61.26		FGF12_HUMAN (1-243): 4.79e-120: 343: 100.00
+	Hs
		1272846 SCN8A_HUMAN (1-2009): 0: 1879: 72.96		FGF14_HUMAN (1-243): 3.37e-109: 316: 70.97
+	Hs
		1055038 SCN5A_HUMAN (3-2003): 0: 1865: 61.26		FGF14_HUMAN (1-243): 3.37e-109: 316: 70.97
+	Hs
		1055036 SCN5A_HUMAN (3-2003): 0: 1865: 61.26		FGF13_HUMAN (1-243): 4.47e-105: 305: 65.74
+	Hs
		1055037 SCN5A_HUMAN (3-2003): 0: 1865: 61.26		FGF11_HUMAN (3-223): 3.75e-102: 297: 60.63