HitPredict

Interactor 1: K1C9 (P35527)
Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)
Gene: KRT9

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 623 Hs			1 217
+	Hs
		359329 K1C14_HUMAN (151-484): 1.87e-149: 441: 55.39		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		580010 K1C15_HUMAN (152-465): 4.48e-147: 435: 55.73		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		280559 KRT34_HUMAN (107-491): 1.38e-144: 426: 36.90		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		445027 K1C16_HUMAN (149-478): 7.63e-142: 422: 54.85		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924493 K1C17_HUMAN (84-476): 1.12e-139: 415: 49.36		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		444346 K1C19_HUMAN (147-473): 7.35e-112: 342: 54.74		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		280492 KT33A_HUMAN (99-480): 6.34e-101: 314: 37.70		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924574 KT33B_HUMAN (112-494): 5.12e-101: 314: 37.50		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924469 KRT83_HUMAN (33-536): 3.41e-88: 284: 21.58		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924576 KRT81_HUMAN (37-551): 8.15e-88: 284: 21.51		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		213936 KRT86_HUMAN (37-509): 4.75e-86: 278: 20.89		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		275168 K1C13_HUMAN (141-478): 7.77e-151: 444: 53.25		GRAP2_HUMAN (3-55): 1.58e-10: 61.3: 39.62
+	Hs
		924470 KRT85_HUMAN (32-524): 9.08e-82: 268: 20.40		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924679 K2C73_HUMAN (38-555): 1.23e-81: 268: 21.78		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Mm
		403444 K1C14_MOUSE (152-465): 4.5e-146: 433: 56.37		SRC_MOUSE (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		280510 KRT34_HUMAN (107-491): 1.38e-144: 426: 36.90		HCK_HUMAN (120-215): 1.21e-12: 68.1: 19.39
+	Hs
		442846 K1C40_HUMAN (80-486): 1.13e-139: 415: 35.12		HCK_HUMAN (120-215): 1.21e-12: 68.1: 19.39
+	Hs
		531551 K2C5_HUMAN (1-468): 2.71e-75: 253: 22.31		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Mm
		403471 K1C16_MOUSE (152-462): 2e-139: 415: 56.27		SRC_MOUSE (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		337481 K1H1_HUMAN (105-479): 5.22e-77: 252: 37.60		ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46