HitPredict

Interactor 1: K1C9 (P35527)
Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)
Gene: KRT9

Interactor 2: SH3G3 (Q99963)
Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)
Gene: SH3GL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	16169070
Identification Methods	two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 623 Hs			1 347
+	Hs
		724061 K1C9_HUMAN (1-623): 0: 667: 100.00		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		359329 K1C14_HUMAN (151-484): 1.87e-149: 441: 55.39		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		580010 K1C15_HUMAN (152-465): 4.48e-147: 435: 55.73		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		280559 KRT34_HUMAN (107-491): 1.38e-144: 426: 36.90		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		445027 K1C16_HUMAN (149-478): 7.63e-142: 422: 54.85		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		924493 K1C17_HUMAN (84-476): 1.12e-139: 415: 49.36		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		444346 K1C19_HUMAN (147-473): 7.35e-112: 342: 54.74		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		280492 KT33A_HUMAN (99-480): 6.34e-101: 314: 37.70		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		924574 KT33B_HUMAN (112-494): 5.12e-101: 314: 37.50		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		924469 KRT83_HUMAN (33-536): 3.41e-88: 284: 21.58		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		924576 KRT81_HUMAN (37-551): 8.15e-88: 284: 21.51		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		213936 KRT86_HUMAN (37-509): 4.75e-86: 278: 20.89		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		924470 KRT85_HUMAN (32-524): 9.08e-82: 268: 20.40		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		924679 K2C73_HUMAN (38-555): 1.23e-81: 268: 21.78		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		531551 K2C5_HUMAN (1-468): 2.71e-75: 253: 22.31		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		924895 KRT82_HUMAN (39-465): 1.23e-74: 249: 20.05		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		359480 K2C6A_HUMAN (2-484): 5e-73: 246: 23.12		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		280786 KRT36_HUMAN (34-465): 1.1e-68: 232: 40.51		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		924575 K1H2_HUMAN (212-534): 8.4e-10: 63.4: 9.37		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		924741 KRT35_HUMAN (212-560): 1.37e-09: 62.6: 10.64		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38