HitPredict

Interactor 1: FBN1 (P35555)
Fibrillin-1 [Cleaved into: Asprosin]
Gene: FBN1

Interactor 2: FBN1 (P35555)
Fibrillin-1 [Cleaved into: Asprosin]
Gene: FBN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.868

The method score is based on:

Property Details
Experiments 18448684, 24035709, 25034023
Identification Methods solid phase assay, molecular sieving, comigration in sds page, 3D electron microscopy, pull down
Interaction Type direct interaction, putative self interaction

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_3~EGF_CA, EGF_CA~EGF_CA, EGF_CA~FXa_inhibition, EGF_CA~TB, FXa_inhibition~FXa_inhibition
Common GO terms GO:0001501 - skeletal system development
GO:0001527 - microfibril
GO:0001656 - metanephros development
GO:0005178 - integrin binding
GO:0005179 - hormone activity
and 25 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 2871
Hs

1 2871
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024