Interactor 1: FBN1 (P35555)
Fibrillin-1 [Cleaved into: Asprosin]
Gene: FBN1

Interactor 2: LTBP1 (Q14766)
Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1)
Gene: LTBP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 12429738
Identification Methods enzyme linked immunosorbent assay, far western blotting
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_3~EGF_CA, EGF_CA~EGF_CA, EGF_CA~TB, EGF_CA~FXa_inhibition
Common GO terms GO:0001527 - microfibril
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005788 - endoplasmic reticulum lumen
GO:0031012 - extracellular matrix
and 2 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 2871
Hs

1 1721
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024